Welcome to the Harvard Aging Brain Study (HABS; NIH-P01AG036694) data request page!

 

The current publicly available data set is v1.00, which includes demographic information, clinical and neuropsychological assessments, as well as regional PiB-PET and structural MRI imaging measurements. It consists of cross-sectional (baseline) data for 284 cognitively normal participants between the ages of 60-90 who have completed baseline visits for the Harvard Aging Brain Study. Over time we will be releasing more data, which will also include T1-structural MR, resting state fMRI, and FDG-PET imaging data.1

 

Specifically, v1.00 release consists of:

Demographic information

  • Age
  • Education
  • Verbal IQ
  • Sex
  • Race
  • Ethnicity

Clinical assessments

  • Clinical Dementia Rating - CDR
  • Mini Mental State Examination - MMSE
  • Geriatric Depression Scale - GDS

Neuropsychological assessments

  • Boston Naming Test (30 Item) - BNT
  • Category Fluency - CAT
  • Digits
  • Digit Symbol
  • FAS
  • Letter Number
  • Logical Memory
  • Spaced Retrieval Training - SRT
  • Trail Making Task - TMT

PiB-PET imaging data

  • 60-minute dynamic with DVR measurements made with the Logan plot method
  • ROI data defined on both the Harvard-Oxford template as well as the Desikan-Killiany atlas from FreeSurfer

MR MPRAGE structural imaging data

  • Processed with FreeSurfer v5.1
  • Regional cortical thickness measures based on the Desikan-Killiany Atlas from FreeSurfer
  • Subcortical volumetric measures

 

Sources

  1. Dagley et al., Harvard Aging Brain Study: dataset and accessibility. Neuroimage. 2017; 144(Pt B): 255–258.