Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance

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Angew Chem Int Ed Engl
2012 Jul 9
51
28
6904-7
10.1002/anie.201201661
Epub Date: 
Friday, June 8, 2012
Journal Articles
PubMed ID: 
22684680

Easy to find: magnetic nanoparticles bearing fluorochromes (red) that intercalate with DNA (green) form microaggregates with DNA generated by the polymerase chain reaction (PCR). These aggregates can be detected at low cycle numbers by magnetic resonance (MR).

Year: 
2012