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Neuroimage. 2009 Sep;47(3):1055-65 doi: 10.1016/j.neuroimage.2009.05.079. 2009 Jun 13.

Brain encoding of acupuncture sensation--coupling on-line rating with fMRI

Napadow V, Dhond RP, Kim J, LaCount L, Vangel M, Harris RE, Kettner N, Park K.

Abstract

Acupuncture-induced sensations have historically been associated with clinical efficacy. These sensations are atypical, arising from sub-dermal receptors, and their neural encoding is not well known. In this fMRI study, subjects were stimulated at acupoint PC-6, while rating sensation with a custom-built, MR-compatible potentiometer. Separate runs included real (ACUP) and sham (SHAM) acupuncture, the latter characterized by non-insertive, cutaneous stimulation. FMRI data analysis was guided by the on-line rating timeseries, thereby localizing brain correlates of acupuncture sensation. Sensation ratings correlated with stimulation more (p

PMID: 19500677
| MGH/HST Martinos Center for Biomedical Imaging

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