AJNR Am J Neuroradiol. 2012 Jun;33(6):E82-4 doi: 10.3174/ajnr.A2701. 2011 Sep 29.

Multimodal imaging of spike propagation: a technical case report

Tanaka N, Grant PE, Suzuki N, Madsen JR, Bergin AM, Hämäläinen MS, Stufflebeam SM.

Abstract

We report an 11-year-old boy with intractable epilepsy, who had cortical dysplasia in the right superior frontal gyrus. Spatiotemporal source analysis of MEG and EEG spikes demonstrated a similar time course of spike propagation from the superior to inferior frontal gyri, as observed on intracranial EEG. The tractography reconstructed from DTI showed a fiber connection between these areas. Our multimodal approach demonstrates spike propagation and a white matter tract guiding the propagation.

PMID: 21960488