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Lancet. 2000 May 13;355(9216):1696-7

Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease

Adalsteinsson E, Sullivan EV, Kleinhans N, Spielman DM, Pfefferbaum A.

Abstract

In patients with Alzheimer's disease, but not in health controls, longitudinal magnetic resonance spectroscopy shows a striking decline in the neuronal marker, N-acetyl aspartate, despite little decline in underlying grey-matter volume.

PMID: 10905250
| MGH/HST Martinos Center for Biomedical Imaging

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