Neuroscientist. 2013 Sep 18;20(3):291-304 doi: 10.1177/1073858413503711. 2013 Sep 18.

Migraine Mistakes: Error Awareness

Borsook D, Aasted CM, Burstein R, Becerra L.

Abstract

Error awareness or detection is the conscious and subconscious processing to evaluate physiological signals that are different from a baseline or homeostatic level. Migraine is a unique neurological disorder in which there are repeated attacks interspersed by attack-free periods. These attacks are dynamic and multidimensional in the sense that sensory, affective, autonomic, and cognitive functions are altered and these changes evolve differently before (pre-ictal), during (ictal), and immediately after (post-ictal) an attack. Thus migraine serves as a model disease to understand how the brain monitors and react to the presence of errors.

PMID: 24047609