Am J Cardiol. 2008 Apr 15;101(8):1127-30 doi: 10.1016/j.amjcard.2007.12.012. 2008 Feb 11.

Relation of the metabolic syndrome to quantity of coronary atherosclerotic plaque

Butler J, Mooyaart EA, Dannemann N, Bamberg F, Shapiro MD, Ferencik M, Brady TJ, Hoffmann U.

Abstract

Although metabolic syndrome (MS) is associated with adverse cardiovascular outcomes, its association with the presence and extent of coronary atherosclerotic plaques is not well described. To assess this relation, multidetector computed tomography-based patterns of coronary plaque were assessed in 77 patients enrolled in the ROMICAT study (age 54 +/- 12 years; 79% Caucasians, and 36% women) and compared between those who did (n = 35; 45%) and did not (n = 42; 55%) have MS. The presence of any, calcified, and noncalcified plaque was significantly higher in patients with than without MS (91%, 74%, and 77% vs 46%, 45%, and 40% segments with plaque, respectively; all p

PMID: 18394445