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Chem Commun (Camb). 2013 Nov 14;49(88):10361-3 doi: 10.1039/c3cc45802d.

Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria

Yuan H, Cho H, Chen HH, Panagia M, Sosnovik DE, Josephson L.

Abstract

Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes, with an [(18)F] labeling option which, when enabled, allows imaging of a cardiac perfusion deficit using PET/CT.

PMID: 24072060
PubMed Entry
| MGH/HST Martinos Center for Biomedical Imaging

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