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Med Image Comput Comput Assist Interv. 2012;15(Pt 2):49-56

Temporal shape analysis via the spectral signature

Bernardis E, Konukoglu E, Ou Y, Metaxas DN, Desjardins B, Pohl KM.

Abstract

In this paper, we adapt spectral signatures for capturing morphological changes over time. Advanced techniques for capturing temporal shape changes frequently rely on first registering the sequence of shapes and then analyzing the corresponding set of high dimensional deformation maps. Instead, we propose a simple encoding motivated by the observation that small shape deformations lead to minor refinements in the spectral signature composed of the eigenvalues of the Laplace operator. The proposed encoding does not require registration, since spectral signatures are invariant to pose changes. We apply our representation to the shapes of the ventricles extracted from 22 cine MR scans of healthy controls and Tetralogy of Fallot patients. We then measure the accuracy score of our encoding by training a linear classifier, which outperforms the same classifier based on volumetric measurements.

PMID: 23286031
| MGH/HST Martinos Center for Biomedical Imaging

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