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Magn Reson Med. 1991 Nov;22(1):154-8

Proton NMR imaging of cerebral blood flow using H2(17)O

Kwong KK, Hopkins AL, Belliveau JW, Chesler DA, Porkka LM, McKinstry RC, Finelli DA, Hunter GJ, Moore JB, Barr RG.

Abstract

Cerebral blood flow was quantitatively mapped by monitoring the cerebral washout of H2(17)O using rapid, single-shot proton NMR imaging. H2(17)O acts as a freely diffusible contrast agent for proton imaging via its scalar-coupled term, enhancing T2 relaxation. Measured values for CBF ranged from 29 to 106 ml/min/100 g over a range of arterial pCO2 between 23 and 81 Torr.

PMID: 1798389
| MGH/HST Martinos Center for Biomedical Imaging

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