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NMR Biomed. 1995 Jun;8(4):149-58

In vivo and in vitro studies of cyclophosphamide chemotherapy in a mouse mammary carcinoma by 31P NMR spectroscopy

Street JC, Mahmood U, Matei C, Koutcher JA.

Abstract

The effect of cyclophosphamide on the metabolic profile of a mammary carcinoma implanted on the foot of mouse was studied by 31P NMR spectroscopy both in vivo and in perchloric acid extracts. The ratio nucleotide triphosphate:P(i) was significantly elevated in cyclophosphamide treated tumours relative to untreated tumours after 96 h in vivo (p

PMID: 8771089
PubMed Entry
| MGH/HST Martinos Center for Biomedical Imaging

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