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J Magn Reson. 1999 Oct;140(2):320-4 doi: 10.1006/jmre.1999.1850.

Single-shot diffusion measurement in laser-polarized Gas

Peled S, Tseng CH, Sodickson AA, Mair RW, Walsworth RL, Cory DG.

Abstract

A single-shot pulsed gradient stimulated echo sequence is introduced to address the challenges of diffusion measurements of laser polarized 3He and 129Xe gas. Laser polarization enhances the NMR sensitivity of these noble gases by >10(3), but creates an unstable, nonthermal polarization that is not readily renewable. A new method is presented which permits parallel acquisition of the several measurements required to determine a diffusive attenuation curve. The NMR characterization of a sample's diffusion behavior can be accomplished in a single measurement, using only a single polarization step. As a demonstration, the diffusion coefficient of a sample of laser-polarized 129Xe gas is measured via this method.

PMID: 10497039
| MGH/HST Martinos Center for Biomedical Imaging

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