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Science. 1982 Nov 26;218(4575):902-4

Deoxyglucose analysis of retinotopic organization in primate striate cortex

Tootell RB, Silverman MS, Switkes E, De Valois RL.

Abstract

We have anatomically analyzed retinotopic organization using the 14C-labeled 2-deoxy-D-glucose method. The method has several advantages over conventional electrophysiological mapping techniques. In the striate cortex, the anatomical substrate for retinotopic organization is surprisingly well ordered, and there seems to be a systematic relationship between ocular dominance strips and cortical magnification. The 2-deoxyglucose maps in this area appear to be largely uninfluenced by known differences in long-term metabolic activity. This method should prove useful in analyzing retinotopic organization in various visual areas of the brain and in different species.

PMID: 7134981
| MGH/HST Martinos Center for Biomedical Imaging

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