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Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4885-94 doi: 10.1073/pnas.1604135113. 2016 Jul 28.

Neural mechanisms of transient neocortical beta rhythms: Converging evidence from humans, computational modeling, monkeys, and mice

Sherman MA, Lee S, Law R, Haegens S, Thorn CA, Hämäläinen MS, Moore CI, Jones SR.

Abstract

Human neocortical 15-29-Hz beta oscillations are strong predictors of perceptual and motor performance. However, the mechanistic origin of beta in vivo is unknown, hindering understanding of its functional role. Combining human magnetoencephalography (MEG), computational modeling, and laminar recordings in animals, we present a new theory that accounts for the origin of spontaneous neocortical beta. In our MEG data, spontaneous beta activity from somatosensory and frontal cortex emerged as noncontinuous beta events typically lasting

PMID: 27469163
| MGH/HST Martinos Center for Biomedical Imaging

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