Research

  • Stroke
    • Patient triage
      • MR WITNESS: Treating patients with unwitnessed strokes with early stroke patterns on MRI
        • MR WITNESS results presented at Late Breaking Oral and Plenary sessions at 2016 International Stroke Conference

        MRWITNESS

      • I-WITNESS: Coming Soon!

         

    • Precision medicine: predicting tissue outcome on an individual patient basis using machine learning algorithms to combine multiparametric MRI

    • Evaluating therapeutic efficacy using statistical algorithms

      2384-93. Epub 2006 Aug 3.

    • Novel MRI markers of tissue viability
      • MR-based oxygen extraction measures in the brain
      • Diffusion tensor and kurtosis imaging

      • Advanced perfusion imaging techniques (dynamic susceptibility contrast imaging and arterial spin labeling)

        173-81

  • Cardiac Arrest
    • Prediction of long-term neurologic outcome in comatose cardiac arrest patients using multimodal techniques (MRI, EEG and clinical exam)

  • Traumatic Brain Injury
    • Mild TBI: Improve diagnosis and prognosis using MRI biomarkers

      resting state

    • Severe TBI: Prediction of long-term neurologic outcome using multimodal technique

Funding

Supported in part by a SPARK grant from the MGH Institute for Heart, Vascular and Stroke Care; MGH Executive Committee on Research; PHS NIH grants R01NS059775, R01NS063925, P50NS05134, U01NS069208, R01NS051412, P41EB015896.