Postdoctoral Fellowship at the Martinos Center for Biomedical Imaging and the Psychiatric Neuroimaging Division of the Psychiatry Department at Massachusetts General Hospital, Charlestown, MA
Project: Development of motion aware diffusion and functional MRI analysis techniques for clinical autism research
PI: Dara S. Manoach, Ph.D.
We are seeking a candidate who combines technical sophistication in fMRI and DTI data analysis with a strong interest in autism research to complement our team of clinical researchers and MRI engineers.
Recent work clearly demonstrates that head motion can give rise to spurious group differences in studies of clinical populations. Our team is developing several technical innovations that will significantly reduce the impact of head motion on fMRI and diffusion acquisition. We are seeking a candidate to work with us to: 1) improve data analysis by making fMRI and diffusion analysis motion-aware using both the in-image data and the motion tracking data and 2) apply these optimized analyses to clinical data. Our goal is to develop a complete acquisition and analysis pipeline that allows us to overcome the artifactual group differences due to motion, and study the true underlying differences in functional and structural connectivity related to autism.
The Research Fellow will be expected to:
1) Assist with setting up the data acquisition to ensure that the protocols are well-designed for the clinical questions;
2) Help with the modification of motion-aware processing tools that work in concert with existing software packages to improve the analysis of fMRI and DWI data;
3) Assist in the processing, interpretation and analysis of the results of both phantom and human studies; and
4) Apply these methods to address clinical research questions in autism.
Our ideal candidate has a PhD in Cognitive Science, Computer Science, Electrical Engineering, or a related field. Candidates with experience in image processing and time series analysis (ideally in fMRI and diffusion data analysis) will be preferred. This position requires strong programming skills, and the candidate is expected to have experience working in C++, scripting languages (e.g., Python), and rapid-prototyping languages for numerical algorithms (e.g., Matlab, Mathematica). Strong communication skills are essential, as the position involves working with an interdisciplinary team of scientists in both MRI physics/engineering and psychology/neuroscience in addition to research coordinators and MRI technologists. Mentoring in clinical research will be provided.
Candidates available immediately will be preferred. Please send (a) CV, (b) statement of post-doctoral and career goals, (c) writing sample (e.g., a published manuscript), and (d) letters and/or contact information for three references to Dara Manoach at email@example.com.
Research Coordinator Position in Psychiatric Neuroimaging at the MGH-Martinos Center
We are looking to hire a college graduate with strong organizational and interpersonal skills as a full time research assistant for several projects investigating the neural basis and nature of cognitive deficits in neuropsychiatric disorders. The primary line of investigation focuses on the contribution of abnormal sleep to impaired memory consolidation in schizophrenia. Another set of investigations involves the use of multimodal neuroimaging to study brain connectivity autism spectrum disorder. The techniques employed include polysomnography (sleep electroencephaolography), functional magnetic resonance imaging (fMRI), magneto- and electroencephalography (MEG/EEG), and diffusion tensor imaging (DTI). Responsibilities are varied and involve working closely with the Principal Investigator, lab mates, and collaborators on all aspects of the research projects. Training in data acquisition and analysis will be provided. Responsibilities include managing patient studies, recruitment and characterization of participants, maintaining accurate records, and assisting with grant applications, human subject applications, and publications. Knowledge of Mac and/or Linux/UNIX operating systems as well as some programming experience are an asset, as is a high level of comfort with novel computer applications and environments. We use Matlab and/or unix scripting in many of our analyses. A background in psychology, statistics, and neuroscience is an asset. A mentored research project is encouraged. The candidate must be mature and responsible with excellent organizational as well as oral and written communication skills. S/He must be able to work independently in a fast-paced environment, juggle and prioritize multiple tasks, feel comfortable working with clinical and non-clinical study populations, working as part of a team and seek assistance when appropriate. This is an excellent research opportunity for someone bound for graduate school in psychology, cognitive neuroscience, or medicine. Position is available starting summer 2014. A two-year commitment is required. Please send a resume, writing sample, and contact information for three references to:
Tessa Vuper (firstname.lastname@example.org) or David Correll (email@example.com)