Measurement of the EEG during fMRI scanning can give rise to image distortions due to magnetic susceptibility, eddy currents or chemical shift artifacts caused by certain types of EEG electrodes, cream, leads, or amplifiers. Two different creams were tested using MRS and T2* measurements, and we found that the one with higher water content was superior. This study introduces an index that quantifies the influence of EEG equipment on the BOLD fMRI signal.
Although sleep is a familiar phenomenon, its functions are yet to be elucidated. Understanding these functions of sleep is an important focus area in neuroscience. Electroencephalography (EEG) has been the predominantly used method in human sleep research but does not provide detailed spatial information about brain activation during sleep.
Newsweek spotlights the Martinos Center's Suzanne Corkin and her work with 'the world's most famous brain' over a span of four decades. The profile follows the recent publication of Corkin's book Permanent Present Tense: The Unforgettable Life of the Amnesic Patient, H.M.
Previously we introduced an automated high-dimensional non-linear registration framework, CVS, that combines volumetric and surface-based alignment to achieve robust and accurate correspondence in both cortical and sub-cortical regions (Postelnicu et al., 2009). In this paper we show that using CVS to compute cross-subject alignment from anatomical images, then applying the previously computed alignment to diffusion weighted MRI images, outperforms state-of-the-art techniques for computing cross-subject alignment directly from the DWI data itself.
Robert L. Savoy, Ph.D., Director of fMRI Education
Bruce R. Rosen, M.D., Ph.D., Director of the MGH/MIT/HMS Martinos Center NEXT PROGRAM: October 26-30, 2020
The early success with what we now know as fMRI was the result of a confluence of factors at the Massachusetts General Hospital, including considerable work with susceptibility contrast and the availability of clinical echo planar imaging (EPI). Just as important, said Kenneth Kwong, one of the originators of the technique, was the “free-wheeling and fertile intellectual environment” structured and encouraged by Thomas Brady and Bruce Rosen at the MGH NMR Center (now the Martinos Center for Biomedical Imaging). The MGH NMR Center was established in 1989 with Brady as founding Director.
